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Vol. 7 (2025): The DEFT facility: An accelerator for very-high-energy electron FLASH radiotherapy—Technical design report

Maria Elena Angoletta et al.

Corresponding editors: Alexej Grudiev and Andrea Latina

The design of an accelerator facility capable of delivering FLASH radiotherapy to large, deep-seated tumours is presented. The facility, called DEFT (Deep Electron Flash Therapy), produces 140 MeV electrons so is capable of treating tumours located at depths up to 25 cm. It is capable of delivering sufficient electron intensity to treat tumours up to 20 cm in diameter, in less than 0.1 s with doses up to 20 to 30 Gy. The full facility, including electron source, accelerator and beam delivery system are described along with extensive performance simulations.

Published: 2025-09-30

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